Oncology
Study links specific gut microbes to endometrial cancer risk—some raise risk, others may offer protection.
New stemness-driven subtypes in ovarian cancer reveal targets to overcome drug resistance and poor survival outcomes.
Bispecific antibody bridging before CAR T-cell therapy appears safe and effective in LBCL, study shows.
AI model predicted 12-month CAR T-cell outcomes in R/R LBCL using pretreatment images with 77% sensitivity.
M-Pola more than doubled PFS and boosted response rates vs. R-GemOx in transplant-ineligible R/R LBCL patients.
C5 DLBCL patients saw better outcomes with Pola-R-CHP vs R-CHOP, per POLARIX trial subgroup analysis.
Mole count and genetics strongly impact mole-linked melanoma risk, while sun exposure affects both melanoma types equally.
Researchers identified 4 genes tied to propionate metabolism to predict head and neck cancer risk and survival.
NF1-mutant melanoma may respond to EGFR inhibitors, offering hope for patients resistant to immunotherapy.
Forty-seven genes were linked to patient survival.
Lower education level was linked to reduced access to mutational testing and clinical trials.
The prospective case series demonstrates the efficacy of the combination in second- and later-line treatment.
Targeted therapies directed toward tumor genotype should be considered in addition to standard-of-care regimens.
New biomarker 2,3,6-trichlorobenzaldehyde shows 95% accuracy in blood tests for early cervical cancer and CIN detection.
Menstrual blood HPV testing shows 100% match with cervical smears—non-invasive, accurate, and preferred by most women.
This was an unexpected finding because mature TLS are typically rare in poorly immunogenic HPV-negative HNSCC.
Tumor mutations were even detected in early-stage disease.
The findings reaffirm concurrent chemoradiotherapy as a cornerstone of treatment.
Patient-derived cells have the potential to enhance drug screening tools and improve patient outcomes.
Researchers identified the pathologic and clinical characteristics of patients who experience disease relapse.
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